Pro-Nox™

What is Pro-Nox™?

Pro-Nox™ is a proven, safe, and FDA-cleared analgesic gas delivery system that uses a 50/50 mix of Nitrous Oxide and Oxygen. Often compared to “laughing gas,” Pro-Nox™ significantly reduces treatment-related pain, stress, and anxiety, promoting a more relaxed and euphoric state without the need for full sedation.

How Does Pro-Nox™ Work?

During your laser or injectable procedure, you are in complete control of Pro-Nox™ administration. With a handheld device and interchangeable breathing circuits for optimal hygiene, you can inhale as needed. The relief you experience is directly related to the amount you breathe in, giving you the power to manage your comfort.

Your Skin Artisans provider has been specially trained to guide you through the process and ensure you achieve optimal comfort throughout your treatment.

What Treatments Can Pro-Nox™ Be Used With?

At Skin Artisans, Pro-Nox™ is a popular addition to a wide range of aesthetic treatments, including:

• Laser resurfacing (such as HALO®, MOXI™, ProFractional®, and MicroLaserPeel®)
• Cosmetic injections, especially dermal filler procedures like lip enhancements

Pro-Nox™ offers an ideal solution for making these treatments more comfortable and stress-free.

Is Pro-Nox™ Safe?

Pro-Nox™ is absolutely safe. It’s FDA-cleared and trusted by over 5,500 medical practices across the U.S. and Canada. Unlike anesthesia, Pro-Nox™ does not cause full sedation. You remain awake, alert, and responsive throughout your procedure.

Pro-Nox™ has been safely used for years in labor and delivery settings, making it a reliable and safe option for aesthetic treatments at Skin Artisans.

What Does Pro-Nox™ Feel Like?

After 5–7 inhalations, most patients describe feeling as if they’re “on Cloud Nine”—lighter, calmer, and much more at ease. Some patients experience a sense of euphoria, mild giggles, or simply feel deeply relaxed. This gentle, uplifting effect is temporary and designed to ease anxiety, pain, and discomfort during your procedure.

Who is a Good Candidate for Pro-Nox™?

Most patients are excellent candidates for Pro-Nox™, especially those who:

• Feel anxious about their treatment
• Have a fear of needles
• Are concerned about discomfort during the procedure

Your Skin Artisans provider will review your medical history to ensure there are no contraindications, such as respiratory infections or pulmonary conditions, that might make Pro-Nox™ unsuitable for you.

Are There Any Side Effects to Pro-Nox™?

Side effects with Pro-Nox™ are typically mild and short-lived. Some patients report feeling slightly lightheaded, “giggly,” or pleasantly “buzzed,” similar to the sensation after a couple of cocktails. You may also notice a temporary deepening of your voice. Overall, most patients just feel relaxed, calm, and ready to enjoy their treatment experience!

Can I Drive Home After a Treatment with Pro-Nox™?

Yes! One of the greatest benefits of Pro-Nox™ is how quickly its effects wear off. Within 10–15 minutes after your treatment, the gas is fully cleared from your system, allowing you to safely drive home, return to work, or resume normal activities.

Will Pro-Nox™ Eliminate All Discomfort?

While we cannot guarantee the complete elimination of discomfort, the majority of patients experience up to an 85% reduction in pain and anxiety with Pro-Nox™. It’s a true game-changer for anyone who feels hesitant or anxious about aesthetic treatments — just a few deep breaths can make all the difference!

What is the Cost to Add Pro-Nox™ to My Treatment?

Pro-Nox™ can be added to any laser or injectable procedure for $125.00.

It’s especially popular during:

• Dermal filler lip enhancements
• Sculptra® treatments
• HALO® and ProFractional® laser resurfacing

How Do I Add Pro-Nox™ to My Treatment?

Adding Pro-Nox™ is easy! Simply let us know when booking your appointment that you’d like to include Pro-Nox™ with your service. We’ll make sure the system is ready and waiting for you at the time of your treatment.

At Skin Artisans, we believe everyone deserves to look and feel their very best—without fear or discomfort standing in the way. If anxiety, fear of needles, or concerns about treatment discomfort have been holding you back, ask us how Pro-Nox™ can help create a more relaxed and empowering treatment experience. We’re here to support you every step of the way toward your aesthetic goals!