As 2026 unfolds, many people are feeling motivated to recommit to their health, focusing not just on weight loss but on feeling stronger, healthier, and more confident in their bodies. For some, that journey includes medically supervised GLP-1 weight loss therapy, like the comprehensive program offered at Skin Artisans. This innovative approach to sustainable weight loss has helped countless patients achieve meaningful results by improving metabolic health, boosting energy levels, reducing inflammation, and restoring a powerful sense of self confidence.
At Skin Artisans, we witness these transformations every day. But as GLP-1 therapies continue to help patients achieve significant, life changing weight loss, another conversation is gaining attention and it deserves just as much care and expertise. For some patients, particularly those over 40, substantial weight loss can be accompanied by changes in facial volume and structure.
Losing 25 pounds or more can sometimes reveal hollowing through the cheeks, flattening of the midface, temple deflation, or subtle sagging along the lower face. These changes may feel out of sync with how vibrant, energized, and confident you feel on the inside. It can be surprising, and for many, frustrating to feel healthier than ever while noticing an aging shift in their face.
The good news is that these changes can be treated and improved during your weight loss journey. With the right expertise, advanced techniques, and a thoughtful, personalized approach, facial volume loss during or after weight loss can be beautifully addressed. The highly experienced nurse injectors at Skin Artisans specialize in restoring balance, structure, and natural looking volume using innovative treatments like Sculptra Aesthetic and Restylane dermal fillers. The result is a face that reflects the same vitality, confidence, and success you have achieved in your body after your weight loss success!
Why Facial Changes Might Occur With GLP-1–Assisted Weight Loss
GLP-1 medications are effective because they promote significant fat loss and metabolic efficiency. However, fat loss occurs systemically, not selectively. (Oh, how we all wish that the fat would just disappear from certain areas of our choice!)
The face relies on a series of discrete fat compartments layered over bone and beneath muscle and skin. These fat pads play a critical role in youthful facial contours, particularly in the midface and temples. When these compartments diminish, the effects can be noticeable, and leave a patient’s face looking flattened and gaunt.
At the same time, the natural aging process itself contributes to:
- Progressive collagen degradation
- Loss of elastin fibers
- Thinning of the dermis
- Reduced skin elasticity
When fat loss from GLP-1 therapy intersects with these age-related changes, the face may appear less supported, even if the skin itself remains healthy.
This phenomenon is not unique to GLP 1 medications. Facial volume loss has long been observed after significant weight loss of any kind. What has changed is our ability to address it in a way that is strategic, subtle, and informed by a deep understanding of facial anatomy and the aging process. While in some cases a surgical procedure such as a facelift may be the most appropriate solution for addressing significant skin laxity, advanced injectable treatments like Sculptra and Restylane can offer dramatic improvements in facial lift, structure, and contour for the right patient.
A Structural Problem Requires a Structural Solution
One of the most common mistakes in post-weight-loss facial rejuvenation is focusing only on surface-level concerns, such as lines or folds, without addressing the underlying loss of structural support. At Skin Artisans, facial rejuvenation is never about overfilling or masking change. Instead, our expert nurse injectors focus on restoring facial architecture and supporting the framework that allows the face to look balanced, lifted, and naturally youthful.
This is why the combination of Sculptra® Aesthetic and Restylane® dermal fillers is so effective after weight loss.
Sculptra® Aesthetic: Collagen Restoration From the Inside Out
Sculptra® Aesthetic is a biostimulating injectable made from poly-L-lactic acid (PLLA), a material used safely in medical applications for decades. Unlike traditional fillers, Sculptra does not provide instant volume. Instead, it works over time by stimulating the body’s own collagen production to enhance the support and structure of your skin.
The Science Behind Sculptra
Once injected, Sculptra initiates a controlled inflammatory response that activates fibroblasts within the dermis. These cells are responsible for producing collagen, the structural protein that gives skin strength and resilience.
Over time, this process:
- Improves skin thickness
- Enhances firmness and elasticity
- Restores foundational support
- Creates gradual, natural-looking volume
Because results develop over weeks to months, the outcome looks completely natural—never “done.”
Why Sculptra Is Ideal After Weight Loss
Post-weight-loss faces often experience diffuse volume loss rather than isolated hollowing. Sculptra excels in these scenarios by rebuilding the underlying collagen matrix rather than simply filling space. That means it can also be injected into key areas where traditional hyaluronic acid filler are not traditionally used.
It is especially effective in:
- The midface
- Temples
- Jawline support zones
Results can last two years or longer, making Sculptra an excellent long-term strategy for patients whose bodies, and faces, are still evolving during their weight loss journeys.
Restylane® Fillers: Immediate Lift, Contour, and Definition
While Sculptra restores collagen gradually, many patients benefit from immediate structural support. This is where the Restylane® family of hyaluronic acid fillers plays a critical role.
Hyaluronic acid is naturally present in the skin and helps maintain hydration, volume, and elasticity. Restylane fillers are engineered with different particle sizes and formation properties, allowing your nurse injector to precisely tailor treatment to each area of the face. Two of Skin Artisans nurse injectors’ favorite products to address facial volume loss after a dramatic weight loss are Restylane® Lyft and Contour.
Restylane® Lyft
Restylane Lyft is designed for deeper injection planes and is ideal for:
- Restoring midface volume
- Enhancing cheek projection
- Re-establishing lift that indirectly improves lower-face sagging
This makes it particularly valuable after facial fat loss related to weight reduction.
Restylane® Contour
Restylane Contour uses advanced XpresHAn Technology™, allowing it to flex and move naturally with facial expression. It is ideal for:
- Refining cheek shape
- Enhancing facial balance
- Creating natural definition without stiffness
Whether used alone or together, these fillers provide immediate contour while supporting the skin’s natural movement and expression.
Addressing Collagen, Elastin, and Facial Fat Loss Together
One of the most overlooked aspects of post-weight-loss facial aging is the combined loss of:
- Facial fat
- Collagen
- Elastin
Sculptra addresses the biological loss of collagen by working gradually beneath the surface of the skin. Rather than creating instant volume, it stimulates the body’s natural collagen production over time, helping to rebuild the skin’s underlying structure, strength, and support. As new collagen forms, the face appears firmer, more resilient, and more evenly supported, with improvements that continue to develop over several months.
Restylane fillers complement this process by delivering immediate results. Formulated with hyaluronic acid, Restylane restores lost volume, enhances lift, and refines contour at the time of treatment while also improving skin hydration. This immediate structural support helps rebalance the face as weight loss related volume changes become apparent.
When used together, Sculptra and Restylane create a thoughtful, layered approach that is especially well suited for treating facial volume loss after significant weight loss. Restylane provides instant correction and visible rejuvenation, while Sculptra strengthens and supports the face from within over time. The result is a more natural, balanced, and long lasting outcome that respects facial anatomy, supports the aging process, and evolves beautifully as the face continues to adjust after weight loss.
Why Trust the Nurse Injectors at Skin Artisans
Restoring facial volume after weight loss requires more than excellent products, it requires exceptional expertise and skill. The nurse injectors at Skin Artisans bring over 100 years of combined clinical and aesthetic experience to every patient interaction. This depth of knowledge allows them to see the full picture: facial anatomy, aging patterns, weight-loss-related changes, and long-term aesthetic goals.
What Sets Skin Artisans Injectors Apart
- Highly personalized treatment planning
Every face is unique. Our injectors develop individualized strategies that prioritize balance, proportion, and natural-looking outcomes. - National trainers and educators
Many of our injectors are national trainers who teach other licensed medical professionals how to safely and expertly inject advanced products like Sculptra and Restylane. This level of leadership reflects deep mastery, not just familiarity, with these treatments. - A philosophy of advanced clinical skill and artistry
Natural results are not accidental. They are the product of precision, restraint, and a refined aesthetic eye. - Care, compassion, and partnership
Our injectors understand that weight loss is deeply personal. Many have walked similar paths themselves. Every consultation is grounded in empathy, respect, and support.
Convenient Locations Across the Minneapolis Area
Skin Artisans offers appointments in several convenient locations throughout the Twin Cities area, including Edina, Minnetonka, and Woodbury. This makes it easy to access expert care wherever you are in your journey!
SCULPT & LIFT: A Special Offer for ASPIRE Rewards Patients
If you’ve noticed facial changes after medical weight loss that weren’t part of your plan, SCULPT & LIFT is a special offer for Galderma (the maker of Sculptra and Restylane) ASPIRE Rewards members that was designed with you in mind!
For a limited time only, patients who treat with both Sculptra® and either Restylane® Lyft or Restylane® Contour in a single appointment can save $150! You’ll also receive a customized plan by your Skin Artisans injector that provides both immediate and long-term rejuvenation benefits. This offer is valid through March 3, 2026. To see if you qualify, click here!
Celebrating Your Transformation—Inside and Out
Meaningful weight loss is never accidental. It represents months of commitment, discipline, and a conscious decision to prioritize your health and well-being. At Skin Artisans, we believe that kind of transformation deserves to be celebrated. You have worked hard to feel stronger, healthier, and more confident in your body, and you deserve for your reflection to mirror that same sense of pride and accomplishment.
Our philosophy is not about changing who you are or chasing trends. It is about honoring the journey you have taken and helping your face reflect the vitality, confidence, and renewed energy you feel on the inside. With thoughtful, personalized care, our goal is to support you in looking like the most refreshed, vibrant version of yourself so that every part of your transformation feels aligned and complete.
Let’s Get Started! Schedule Your Complimentary Consultation
Whether you are:
- Exploring GLP-1 medically assisted weight loss
- Actively losing weight through diet and exercise alone
- Or noticing facial changes after a significant weight loss
Our expert team would be honored to walk alongside you, offering guidance, support, and expertise at every stage of your journey.
Schedule a complimentary consultation at Skin Artisans to discuss GLP-1 medically-assisted weight loss and facial rejuvenation with Sculptra® and Restylane®. Together, we’ll create a plan that supports your transformation, beyond the scale and well into 2026!
Call (952) 767-3163 to schedule or BOOK ONLINE!
